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KMID : 0351619630040010109
Kyungpook Medical Journal
1963 Volume.4 No. 1 p.109 ~ p.113
A SMALL COLONY VARLANT OF CRYPTOCOCOUS



Abstract
A petite like small colony of cryptococcus is isolated from the stock culture, and this is studied for its morphological and biochemical characterics by comparing it with normal colony.
1) This small colony differs from the ordinary form of variants in that, it is segregated into both normal and small sized colony by subculture.
2) Neither the effect of PH nor the range of temperature affect the growth of this variant significantly.
3) The growth rate of this varinant is significantly slower both in the liquid medium (by turbidmetry) and on the solid medium(by colonial diametry) than the normal colony.
4) With the addition of amino acid, other than tyrosin, serine, histidine and lysine, this variant is able to grow in the Davis&Mingoli¢¥s synthetic medium.
5) The biological characters, such as sugar assimilation and enzyme activity, are not different from the normal colony.
(Author¢¥s abstract)
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